I have been on Remicade for over 6 years with good results. I have RA, UC, and Crohns. I recieve an infusion every 4 weeks. Lately I have developed bladder spasms and pain. I always assume it is drug related since I take so many meds. I have been to the doc 2 times already. No infections. Change of diet doesn't help.I have discontinued most of my meds in an effort to discover the problem. Nothing changed.