I have gained about 35 lbs since being put on Cymbalta, but it causes DECREASED appetite. I asked a pharmascist and there is only a 1& percentage on this. I know about Abilify that Im on too. I do not want to know all the side effects of Cymbalta. I would like to no if anyone, anyone has experienced this problem. I am also on a slimfast diet for almost 1 month and haven't lost 1 lb. I can not excercise right due to a bad back and sciatica. Please can someone who has experianced this only with Cymbalta answer this question. Thank you.
Has anyone gained weight while on Cymbalta?
- Asked
- 4 Sep 2011 by Anonymous
- Updated
- 6 Aug 2013
- Topics
- cymbalta, obesity, weight
Added 6 Sep 2011:
LISTEN GUYS it may be likely for sure the Abilify is doing this to me. I see in some of your comments that you have been on it with the cymbalta too and has gained weight. 7% of people gain weight with Abilify.
Responses (4)
Hey Eclipse,
I gained weight while on Cymbalta and Abilify, but I wasn't watching what I was eating either. Once I reduced my calorie intake drastically, I have been able to lose the weight I gained. I have 10 more pounds to go and it ain't coming off easy. Wish I had a better answer for you. I switched from Cymbalta to Pristiq with great results. That is when I started losing the weight with dieting.
Best wishes,
Laurie
Hello Eclipse2! I feel your frustration. A lot of the SSRI'S can cause weight gain, unfortunately. I am on Zoloft and have gained 40 lbs. within a year. I continue taking it because it controls my symptoms of Depression and Anxiety.I was on Ambilify but went off as soon as I found out that you can gain weight on it also. A friend of mine has gained weight on Cymbalta. Everyone's chemical composition is different so weight gain may not be an issue for everyone. I just know that there is a high incidence of weight gain on these meds. I wish you the best! Sweetie Pie
I can't eat on Cymbalta or Abilify. Lost about 40 lbs now from it. I gag down a meal probably every other day anymore. I was, however, on Seroquel for a month and all I did was eat and be a zombie, gained five pounds over a one month period. Everyone reacts differently to medications, there is no way anyone can tell you what will or will not cause which, if any, side effect(s).
Ton not tin. Lol

Further Information
- Cymbalta Information for Consumers
- Cymbalta Information for Healthcare Professionals (includes dosage details)
- Side Effects of Cymbalta (detailed)
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thank you Laurie
Hi Eclipse and Laurie,
Me too. I gained on the combo of Cymbalta and Abilify. I stopped the Abilify about a year ago. Over the course of two years I gained probably around 40-45 lbs. I also have had health problems and a buncha surgeries. At any rate, I started Weight Watchers about 6 months ago in earnest and have lost over 20 lbs. I have to exercise and watch what I eat, or else I"m in trouble again. :) It feels better to be lighter.
I've gained about 35lbs too. I take alot of meds but think it's the Cymbalta. Can't really do much excercising because I have RSD but try to walk as much as possible and I watch what I'm eating but can't get it off either. I've never been this heavy :-(
Walking counts as exercise. :) That's all I do. Some days just for ten minutes.
I just started n cymbalta I hope it doesn't make me gain more wait as well I gained 60lbs when my dr put me on amantedine for an alternative for ms treatment when I couldn't get insurance to help me with the ms that was in a 1month time I like hw cymbalta is helping me nly been on it a couple months thank you for putting this post up I appreciate it alot
Hey litlmommag,
Not everyone gains weight on Cymbalta and really if you watch your calorie intake and burn more than you consume you should be fine. Good luck on the new med.
Laurie
Thank u laurie all these meds are pretty much nw making me not wanna eat at all not hugry trying t eat something cause I know I should thanks again
Hi litlmommag! Nice to meet you!
I take 120 mgs of Cymbalta for chronic pain daily & can't say that Cymbalta has increased my weight. I am heavier now but my weight goes up & down with my swollenness. I don't exercise or walk due to my pain. Cymbalta had suppressed my appetite for many weeks. I'm just starting to feel the sensation of hunger now.
Best of health to you! from Wendy :)
Good luck Eclipse! I hope you're feeling starting to feel better!
from your friend, Wendy :)
Thanks again laurie and wendy from jaime litlmomma g