Prazosin was prescribed for my PTSD nightmares. Immediately, I began to experience severe pain and swelling in both knees, so we cut back from 2mg to 1 mg. The problem continued so we stopped altogether. It's been several months and I'm still having the knee problems. I've been with this doctor for over 10 years so he knows my medical history and he still feels uncomfortable associating my knee problems (which I didn't have prior to this medication) with Prazosin. I've gone from being pretty athletic to barely able to climb stairs. Any advice?