Hi and Good Morning- I was just taken off of my 2 year maintenance of Rituxan. The reason was after receiving 4 treatments I started having questionable neurological issues. Nothing major. The oncologist sent me to have a brain scan. A neurologist read it an said i had too much white matter showing up. So I went for a spinal tap to be tested for MS and the very scary brain virus PML. Both came back negative. The oncologist said no more Rituxan and i will get a repeat scan of my brain in 3 months to see if there are any changes. So my question is, has anyone ever had this issue? Does anyone know if Rituxan causes this "White Matter" ?? Thanks for any help... Rosemary