I have had Crohn's disease for 8 years now. I started on Remicade at Mayo Clininc and did very well with this drug for almost 4 years. I was in remission for almost 3 years with the Remicade. When the Remicade became less effect I was switched to Cimzia shots every 2 weeks. I am also taking Entocort along with the Cimzia. I have tried every oral medication for Crohns and Ulcerative colitis with little sucess. I was wondering if anyone has stopped Remicade and switched to a different medication and then switched back to Remicade if it was more sucessful the second time around?