I have been on glipizide XL for 6 months. After being taken off Actos I was given Metformin again, this time the extended Release and had the same really bad side effects. Then put on Trajenta and blood sugar kept going up.Then put on Glipizide.I also have GERD and take Prilosec; PA thinks Prilosec is causing tablet not to dissolve while GI Doctor says no, Prilosec would not do that. Anyone got an answer?