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Can I have a glass or two of wine 5 to 6 hours before taking a 50mg zoloft?

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wannabbetter 1 Apr 2016

It is not really recommended and the wine can make the Zoloft less effective. However, if I had 1 or 2 glasses of wine with 50 mg Zoloft I had no problem. I would also try to drink very slowly & also alternate w/water. If you could get by on just one glass of wine that probably would be better than 2. Also, don't drink on an empty stomach.

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