I've been treated for giant cell with prednisone for 3 months. Every time I try to taper, my blood work spikes and I'm back up on 50 mg of prednisone again. I have found ways to cope with all the side effects except for being irritable and volatile all the time! I've tried exercise, mindfulness tapes, tai chi, but nothing helps. What have people found helpful in dealing with the emotional effects of this drug?