I am afraid of gaining weight which has already happened. The Trillinex gave me monumental headaches daily and dehydration. Stay in a dark room headaches. Trying Rexuti has now first week has constipated me. Seems like a good effect but I have ulcerated colitis and that could send me back to the hospital. I have been suffering with at least depression and anxiety and been on meds since my early 20's. So I have tried everything. Some worked for a while, some not at all or other severe reactions. Can't fit in any of my clothes and I have always been tiny. As a professional woman, it's unacceptable, just like the major depression. Any suggestions?