... and depression having started taking Effexor almost 5 weeks ago. I moved from 75mg to 150mg after the first week and then added Valdoxan at 12.5mg for the first week and now 25mg for the last two weeks on the advice of my Psychiatrist. I also have Bromazapam 3mg to take as and when the anxietly gets too much. I have had 2-3 days when I have started to feel really good but then gone to bed only to wake up feeling horrible and anxious once more. Can anyone give me something positive to take out of their experiences on Effexor as at the moment, I am finding it so hard to continue to believe and wait for it to kick in and work?