I was on 150mg effector 3/yrs now dr uped it to 225mg I've been taking for about a week at 225mg how long does the extra 75mg take to kick in feel better? I also take 15mg of remron to sleep works great been on that for 16yrs.. The last 3 days I have taken 1x a day 0.5mg Xanax to relax is that ok? I'd like some help as I feel like I'm at the beginning again it's tough to enjoy or plan for anything.. Drive, be sociable just wanna live again I HATE THIS DISABILITY!! Any help would be appreciated thank you..