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Is formulation of loratadine sustain release tablets are possible?

Responses (2)

kaismama 15 May 2013

I have read and reread your question but I still don't understand what you are asking?

amalnath 16 May 2013

No need to formulate loratadine in sustained release forms. The mean elimination half-lives found in studies in normal adult subjects were 8.4 hours (range= 3 to 20 hours) for loratadine and 28 hours (range= 8.8 to 92 hours) for the major active metabolites (descarboethoxyloratadine). So loratidine provides prolonged effect.

ankit88 16 May 2013

but sir there was already floating tablet was available for loratadine.so how can we say that there is no need to formulate sustain release tablets?

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