I had side effects from the AT but I am on Toviaz. Since I also have Fibromyalgia and IBS I was going to stop the Toviaz and try the AT for all 3 problems. Hoping to cut out the side effects of headache,dry mouth and more from the Toviaz. When I added the AT the side effects are so bad I ended up with a severe migraine. Would be much better to try the Amitryphiline without bring on any anticholernergics. Basically looking to see what kind of strength people ate taking to treat there IC and frequency.