These should only be used together if absolutely necessary, as there is potential for a major interaction between these. Plus your doctor should monitor you regularly.
The link below explains the interaction in detail.
I currently take 80 mg Fluoxetine 1x daily with dinner and 100 mg of Trazodone 1x daily at bedtime. I have been on this combination for almost two weeks now and have had no problems. The Fluoxetine takes care of most of my depression/OCD and the Trazodone allows me to sleep thru the night.
Bottom line... its the prefect combination for me!!! :-D
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