... Has anyone else had to readjust their Prograf amount after being cured? I am 17 years out from my liver transplant and I took Prograf 1 mg in the am & 1 mg in the pm for all 17 years. Now since I am cured of hep C, I am up to 3mg in the am and 3mg in the pm and I am still not up to the lower level of tacro in my system. Right now my Prograf level is around 4.2 . With the guidelines of >5 <20. I am real jittery on this much tacro.