... Esophageal Cancer resulting from Barretts Esophaghus which I fortunately watched annually, but still had to endure surgical removal of my esophagus, and while I do virtually everything recommended, I still have a problem and fear of aspirating stomach acids. The Omeprazole works, but I have to take it twice a day 20mg ea. I would like to know if anyone has successfully completed their Harvoni treatment while on omperazole. I have searched the groups and cannot find the answer. Thanks to all for sharing. An Amazing group of people. Thank you