I’ve been diagnosed with MDD and Mixed Moods. I’ve taken numerous drugs over the past several months and nothing has helped. I am beyond frustrated. Although I’ve seen some improvement with Lamictal, I have a long way to go. I’ve read it can take up to a month to feel better once reaching the therapeutic dosage. I would appreciate knowing if this was the case for anyone. So many people swear by this drug. I’m trying to remain hopeful (only on day 3 of 200mg). Thank you:).
Finally made it up to 200mg of Lamictal. When will the depression lift?
- 15 Jul 2018 by FrustratedCDM
- 5 August 2018
- lamictal, depression, bipolar disorder, major depressive disorder, drug
Added 15 Jul 2018:
I also take 20mg of Viibryd and 150mg of Seroquel at bedtime to help sleep.
Hi, Frustrated! Understandably you're frustrated... everyone wants to feel better overnight but it takes these medications time to become fully effective:
"Sleep, energy, or appetite may show some improvement within the first 1-2 weeks. Improvement in these physical symptoms can be an important early signal that the medication is working. Depressed mood, anxiety, and lack of interest in activities may need up to 6-8 weeks to fully improve."
Give it the needed time and try to be patient and positive. The end results will be worth the wait!
Best regards, Wildcat
Hello Frustrated! I read your post & I feel the exact same way. I increased my dose of Lamotrigine to 200 mg on July 13th, so I am on my 3rd dose today. I have never felt more depressed in my life. They think I have what’s called cyclothymia. I have had bouts of depression every 5-6 months lasting about 3 months each time over the past several years, but I feel the bouts get worse each time. I have been on multiple medications but none of them would ever keep me out of the depression. Being on Lamotrigine has been tough & I am so scared it’s not going to work. I feel so foggy in my brain and it just feels shut off, making it very hard to function especially with work & my social life is in the dumps right now bc it’s hard to face people like this. I know my psychiatrist says this Med is really good but takes a lot of patience bc of the titration process. Good luck to you & I truly hope your depression lifts soon!
- Lamictal Information for Consumers
- Lamictal Information for Healthcare Professionals (includes dosage details)
- Side Effects of Lamictal (detailed)
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