... with anxiety and agitation, short tempered? A 100 mg per day increase does not make me tired, it makes me irritable and anxious
Fibromyalgia - I have been increased on my Lyrica from 100 mg BID to TID. Has anyone had trouble?
- Asked
- 28 Jul 2016 by John McAvoy
- Updated
- 1 Aug 2016
- Topics
- lyrica, anxiety, diabetic nerve damage, persisting pain, shingles, agitation, fibromyalgia, neuralgia, diabetic neuropathy, postherpetic neuralgia, neuropathic pain
Responses (2)
Hi John,
Yes anxiety, agitation,depression, mood changes are all common side effects.
You do need to take them seriously because they can escalate. If the change was just increased it may subside once your body adjusts.
My problem was that I didn't think it worked. I was gaining weight but not able to lose it. My knees started to take the brunt and I had trouble walking from the pain. I got off of it.
I totally believe that a med should be definitely working if I'm going to take it long term.
Good luck...
Don't be influenced by all the glitzy commercials with so many positive results. It's a big money making drug. Doctors like to prescribe it because it's not a scheduled drug such as opioids so they don't get red-flagged.
Don't be afraid to tell your doctor that it's not working or the side effects are too troublesome to stay on. There are options.
Good luck...

Further Information
- Lyrica Information for Consumers
- Lyrica Information for Healthcare Professionals (includes dosage details)
- Side Effects of Lyrica (detailed)
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so far, not really. it has only been a week so I'll give it a few more.