I have fibromyalgia and Graves Disease. I have been taking prednisone 10mg for over three years now. I started at 180 and now am 210 and increasing. I talk to my doctors about the weight gain. Alli seems to not work and I am feeling just awful about the weight gain but they tell me it is to be expected. The pain causes me not to work out. Does anyone else have the weight gain with the prednisone and if so how do you bring it down? Happy Thanksgiving everyone