... actually be very painful. My pain dr prescribed a fluticasone spray. I spray it on the area I am going to put my patch on and let it dry. It is supposed to be sprayed into the nose. When my Dr first prescribed it and said "put on skin," the pharmacist thought my Dr. was insane and called to make sure he knew what he was doing. If your Dr prescribes it, make sure he or she puts "used as directed" on the prescription. Mine with insurance is about $30, but it lasts for a very long time.