He is now complaining that he can't sleep. My question is, is salicylic acid a stimulant when ingested?
Salicylic acid is chemically related to Aspirin (originally derived from willow bark) and behaves in the human body in a similar way (analgesia, fever reduction). While some people are known to have sensitivity issues with Aspirin, insomnia is rare.
8 cases of insomnia were reported to the FDA between 2004 and 2012 out of 259 reports of any side effect from Salicylic acid/ (giving it an incredibly good safety/side effect profile). An insomnia incidence rate of ~3% in 259 people in a country of over 300 million. Does your father have known adverse reactions to Aspirin?
Asacol causes insomnia, up to 2% of people taking it. It does not specify which ingredient causes it.
Very common (10% or more): Headache (up to 35%)
Common (1% to 10%): Dizziness (up to 8%), lightheadedness (8%), faintness (8%), tinnitus (less than 3%), vertigo (less than 3%), migraine (2% or greater), paresthesia (up to 2% or greater), insomnia (up to 2%)
Rare (less than 0.1%): Benign intracranial hypertension (at least 1 case)
Postmarketing reports: Systemic lupus erythematosus, peripheral neuropathy, Guillain-Barre syndrome, transverse myelitis, somnolence, tremor, hyperesthesia, tinnitus, vertigo
A 23-year-old female with ulcerative colitis who had been taking 400 mg mesalamine tablets three times a day developed benign intracranial hypertension. The examination disclosed benign intracranial hypertension that resolved when mesalamine was discontinued and recurred when the drug was restarted.
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