Try to space it out as much as possible ... maybe 8 to 12 hours at least. But if absolutely necessary as sometimes they work better in combination, adjust the doses and you could give it sooner. The link below states the side effects ... so check for drowsiness, etc.
- Zyrtec Information for Consumers
- Zyrtec Information for Healthcare Professionals (includes dosage details)
- Side Effects of Zyrtec (detailed)
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