I've been on Effexor for several years and have had good luck. I started at 75mg and eventually was at 150mg for a few years. I recently have had some pretty bad panic, anxiety issues and requested I move up. So, currently I'm on 159mg + 37.5 mg and hoping this will help. I'm on day 11 and have had quite a few very bad days, should I expect the typical 2 to 3 weeks to feel better?