im on an SSRI (zoloft, totaly took care of depression) and an NDRI (wellbutrin, only been 3 weeks so no signs of improvment have started obviously), and i dont understand how norepinephrine (so closely related to adrinaline) will slow any part of the body down. I read in my bio psychology book that it has very few (but some) inhibitory functions but it didnt explain how and i couldnt find it online
Exactly how does norepinephrine treat anxiety? it seems like it would be causing excititory effects?
- 19 Nov 2009 by Psychmajor
- 23 November 2009
- wellbutrin, zoloft, depression, anxiety, panic disorder, social anxiety disorder, generalized anxiety disorder, norepinephrine, anxiety and stress
Norepinephrine is a tricky neurotransmitter. It can cause excitatory effects but not always. Depends on the individual, of course.
For example, I tried Strattera (I have ADHD) and it made me tired and spacey as hell. I gained 20lbs on that med. And it's exclusively a Norepinephrine Reuptake Inhibitor.
Could be that Zoloft isn't working for you. What is your Wellbutrin dosage? Maybe your meds are just not right yet. I'd recommend talking with your doctor about the lack of improvement and trying other meds. How many other SSRIs/SNRIs have you tried?
Medications are prescribed in an effort to return the brain’s neurotransmitter status to normal. Much like a physician may prescribe a medication to lower your cholesterol or increase another body chemical, mental health professionals are concerned with returning your neurotransmitter levels to normal.
Medications for mental health conditions work in several ways:
· Some imitate the neurotransmitter, triggering a response as though the original neurotransmitter were present
· Some block the neurotransmitter from being absorbed by the surrounding neurons, known as blocking the reuptake. Reuptake inhibitors block the reabsorption/reuptake of Serotonin or Norepinephrine and thus make more neurotransmitter available
· Some force the release of the neurotransmitter, causing an exaggerated effect. Cocaine does this to Norepinephrine and Dopamine while MDMA (Ecstasy – a club drug) does this to Serotonin.
· Some increase neurotransmitters known to slowdown or reduce the production of other neurotransmitters.
· Some block the release of neurotransmitters completely
· Some interfere with the storage of neurotransmitters, allowing them to come out of storage and lose potency
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