I read one review saying this medication helped reduce symptoms of Pemphigus. I have a serious case of OCP (Ocular Criticatial Pemphigoid) which is related to Pemphigus. My doctor put me on a regimen of Methotrexate 26 weeks ago. The OCP has quickly progressed to what is termed late Stage III. The next stage (IV) is when my eye(s) become(s) blind. I've read over 50 publications written the past 40 years with most describing unsuccessful treatments of OCP. However, I've seen only one study which used Rituxan combined with IVIg infusions that were successful in preventing the participants from losing their eyesight. Does anyone know if Rituxan can help my OCP?