In Aug 2013 new gyne gave me a sample of Minivelle (Estrogen) for severe, debilitating hot flashes. Three days later my knees were hurting and crunching when I walked. They began to swell. I now have Psoriatic Arthritis. I can not walk without a cane. When I wake up it is horrible-my fingers are like sausages, I am so stiff I can not walk. I have pain standing, sitting. Showering is a chore. My life is forever changed. I know this is estrogen related, this is not a coincidence. The hot flashes I suffered with for 7 yrs are gone. I have researched online and have found a few mentions of estrogen and psoriatic arthritis but nothing substantial. Why? Why is this not on the MD's radar? Please-anyone else experience this?