I have done 1 month of cipro, 1 month of doxycycline, 1 week of bactrim. 1 dose of azithromycin. I occasionally take ibuprofen. Nothing has fixed this issue. It gets worse when sitting or standing. Urination and ejaculation seem to reduce pain slightly. Blood test done showed elevated WBC's. 2 urine tests were done and both were negative. The ultrasound showed changes in vascularity in the epididymis. Physical examination revealed epididymitis.