Am tapering off pristiq and onto lexapro for anxiety. Am also on mirtazapine 45 mg. I'm done with the pristiq and am on effexor er 150 mg and the lexapro is at 5 mg, will be increasing itto 10 mg and decreasinf effexor to 75 mg in a couple of days. I was sleeping soundly on pristiq and mirtazapine but withthese med changes im up early. 3 am today andits only 7 now. Is the sleeplessness temporary? I am so miserable and need encouragement to get through this change to lexapro (will stay on the mirtazapine). Also im still anxious during the day. The increase in lexapro should help that right? Thanks for your help and encouragement.