Hello Tammyjo1. The best thing is to call your pharmacist and tell them exactly how long the medicine has been out for and the color of it. I use the SureClick and it does not state on any sites how long it can stay out for but to only let it warm up 15 - 30 minutes before you inject it. Much better to be safe than sorry. Good luck.
- Enbrel Information for Consumers
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