Amitriptyline HCl is an antidepressant with sedative effects. Its mechanism of action in man is not known. It is not a monoamine oxidase inhibitor and it does not act primarily by stimulation of the central nervous system.
Amitriptyline inhibits the membrane pump mechanism responsible for uptake of norepinephrine and serotonin in adrenergic and serotonergic neurons. Pharmacologically, this action may potentiate or prolong neuronal activity since reuptake of these biogenic amines is important physiologically in terminating transmitting activity. This interference with reuptake of norepinephrine and/or serotonin is believed by some to underlie the antidepressant activity of Amitriptyline.
- Elavil Information for Consumers
- Elavil Information for Healthcare Professionals (includes dosage details)
- Side Effects of Elavil (detailed)
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Posted 21 Dec 2009 • 1 answer
Posted 9 Jun 2010 • 1 answer
Elavil in the past was a wonderful sleeping pill for me. then, in the midst of rx oxys etc it seemed
Posted 14 Feb 2011 • 3 answers
I've been presc. elavil for vascular headaches(subarachnoid hemorrhage10 yrs ago) will it work/safe?
Posted 18 Apr 2012 • 2 answers
Posted 16 Sep 2013 • 1 answer