Amitriptyline HCl is an antidepressant with sedative effects. Its mechanism of action in man is not known. It is not a monoamine oxidase inhibitor and it does not act primarily by stimulation of the central nervous system.
Amitriptyline inhibits the membrane pump mechanism responsible for uptake of norepinephrine and serotonin in adrenergic and serotonergic neurons. Pharmacologically, this action may potentiate or prolong neuronal activity since reuptake of these biogenic amines is important physiologically in terminating transmitting activity. This interference with reuptake of norepinephrine and/or serotonin is believed by some to underlie the antidepressant activity of Amitriptyline.
- Elavil Information for Consumers
- Elavil Information for Healthcare Professionals (includes dosage details)
- Side Effects of Elavil (detailed)
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Posted 9 Jun 2010 • 1 answer
I've been presc. elavil for vascular headaches(subarachnoid hemorrhage10 yrs ago) will it work/safe?
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