wow! I have never heard of such thing. I have been taking Effexor xr for about 4 years and I have not noticed any improvement. Perhaps my joint and back problems are too severe... I have taken antidepressants for the last 15 years and I have been changed from one to another as they become more useful to treat PTSD. Perhaps in mild cases of joint pain it may help, but I would assume that it has to do with the fact that stress and anxiety can worsen the pain experienced. Good luck to you,
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