... Recently, I came off the Rexulti and I am only on Cymbalta. We just increased dose to 90 mg, however without the Rexulti it doesn't seem to be working. I wonder is Effexor XR and Cymbalta too similar and so I will not respond to the Cymbalta?
Agreed 100% with your other poster! Cymbalta just about ruined me!!! I know we are all different but, unless you are so incredibly depressed that you want to feel NOTHING and for me it got to be nothing to the point of extreme withdrawal, no emotion and MANY physical symptoms that no decision could figure out and it took me to finally refusing to stop taking it to get my life back. Effexor and cymbalta are both SNRI's and my dr actually after LONG conversations and a lot of me reading and even going off all meds for a while decided to go to Effexor bc it had worked very well for me many years ago. I also was worried bc I thought they were very similar and he and another doctor said in some ways they are but, can act very different in the brain. So, I went ahead an very cautiously bit the bullet and have been back on Effexor bc it worked great for me years ago before popping out. However, cymbalta...
STOP!!! I wouldn't recommend this med to anyone unless you have taken every single other choice out there 1st!!!
I have taken quite a few and most worked well for me for a few years before loosing affect and I can tolerate most any meds but, that one ruined me for about 5 years.
Hi, Brenla! Cymbalta and Effexor are two entirely different drugs but in the same SSNRI class. The fact that the Effexor pooped out on you wouldn't necessarily mean that would cause the Cymbalta not to work. It's possible that you just aren't responding to the Cymbalta because not every person responds the same to every drug.
Why did you stop the Rexulti? Many treatment resistant people need the addition of an antipsychotic in addition to their prescribed antidepressant.
You are on a pretty hefty dose of Cymbalta but it can take as long as 4 to 6 weeks to feel the full benefits. If after a fair trial you're still doing poorly it's time to re-evaluate and possibly try another antidepressant or add an antipsychotic again.
Regards and best wishes. Wildcat
- Cymbalta Drug Information
- Effexor Drug Information
- Effexor XR Drug Information
- Rexulti Drug Information
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