My ongologist has prescribed Effexor XR to reduce the hot flashes I get due to taking Tamoxifen. 150mg Effexor XR are helping only a little w/the hot flashes. My questions is: I've never been a depressed person, but since taking Effexor XR I seem to be "blue" or down-spirited alot. Can this be a side-effect of this med? I thought anti-depressants were to make you not depressed.