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Inactive 17 Jan 2013

Hello ellinam. The side effects can run high (negatively) to this combination. The physician, in regards to the diagnosis would/will perscribe accordingly. Regards pledge

Inactive 18 Jan 2013

Interactions between your selected drugs

Major: Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit

sertraline ↔ venlafaxine
Applies to: Zoloft (sertraline), Effexor XR (venlafaxine)
Talk to your doctor before using sertraline together with venlafaxine. Combining these medications can increase the risk of a rare but serious condition called the serotonin syndrome, which may include symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. You should contact your doctor immediately if you experience these symptoms while taking the medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs.

Pansy404 18 Jan 2013

I am wondering why a doctor would prescribe two anti-depressants together. Do they think they will be more effective for your problem?

navygirl1 20 Jan 2013

this combo wouldn't be prescibed together. i have taken them both. but i taken zoloft with bupropion/wellbutrin not with effexor

PoisonAlice 21 Jan 2013

Sometimes when switching from one antidepressant to another, they'll lower the dose of your current antidepressant while introducing a new one slowly and with small dosage increments with increases that coincide with dosage decreases of the old antidepressant. That way, there's no withdrawals from the old drug, and low possibility of serotonin syndrome. But there's also some doctors that figure hey, if one's not working for someone, lets try 2 or 3 together and see if that works, kind of like throwing spaghetti at the wall to see what sticks, the worst practice in medicine, IMO.

Pansy404 21 Jan 2013

Ellinam, can you update us as to what anti depressant you are taking now. If you are taking Effexor and Zoloft together, what dosage are you taking? Like Alice says perhaps your doctor is slowly switching you from one to the other.

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