Recently I have had a big decline in the effectiveness of Effexor XR 300 mg daily. I hit rock bottom while still on the medication. Does there come a time that my body/brain is so used to this medication that it does not work anymore.
Hi, My! Unfortunately, it's not at all uncommon for antidepressants to "poop out" after long term usage... and 10 years is a long time. I don't know why, but I know they do. My Effexor pooped out after about seven years.
You could ask your doctor about an add-on like Abilify or Rexulti which might booster the Effexor's effects, but you may need to consider switching to a different antidepressant.
Too bad because it seems it worked well for you for so long.
Best regards, Wildcat
- Effexor XR Information for Consumers
- Effexor XR Information for Healthcare Professionals (includes dosage details)
- Side Effects of Effexor XR (detailed)
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