My legs burn like acid and I have sever pain behind my knees and groin. Pitting edema in shins. I've been checked for blood clots and have none according to the ER doctor. C
It's possible, look at this, hope it helps:
It's not likely that Effexor is causing your problem. Don't just go to an ER doctor, go to a doctor who will do more than check your immediate problem. Do you have a family doctor? That would be a place to start. Is this a new or ongoing problem? Tell the doctor everything you are dealing with, let him/her advise you where to go from there.
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