I've been on Efexor for depression and anxiety for 3 weeks and had a sever drinking problem. My drinking was mostly self medicating. I've been clean for over 4 weeks. Last night I tried drinking 3 shots of vodka over the course of a few hours. It felt unplesent. In fact I just wanted it to end. The two more were just to see if I needed a little more. It only kept the unplesent feeling going longer. Did any one else have this reaction? I doubly now never want to drink again. Tithe best of my knowledge Effexor is not recommended as a treatment for alcohol abuse, but it is having that effect on me.