Recently our pharmacy sold to a major chain and my prescription was transferred. After a couple weeks I noticed some issues I hadn't encountered in the past couple years since starting this prescription. There wasn't the usual amount of fluid shed, gradual weight creep and perceived fluid retention in legs, having cramps in my left calf and numbness in my left toes, chest congestion like I hadn't had since before the prescription and very interruptive sleep. It occurs to me that these issues arose since refilling the prescription with the new chain store. The change seems almost immediate since using the chain store Furosemide 20MG. Can the effectiveness and quality vary from one source to another?