My sister was started on Cyramza last week, in addition to Taxol, for her recurrent metastatic esophageal junction cancer. She has already undergone chemo, radiation, surgery to remove tumor with a stomach pull through. She is doing pretty well but now has two metastatic lymph nodes at the porta hepatis. I would like to know if anyone has had "good" prolonged results with Cyramza. Thank you
How effective is Cyramza for cancer remission?
- 19 Jan 2015 by Kimnethercutt
- 19 January 2015
- taxol, cancer, gastric cancer, surgery, radiation, cyramza
Added 20 Jan 2015:
My sister was told she is receiving palliative care at this point. Just hoping that the Cyramza will enable her to receive palliative care for a Long time.
It was just approved in 2014, and approved for use in aggressive cancers 12/12/2014. So we're talking pretty new here.
I am very sorry to tell you this. Cyramza is very new and was approved by the FDA on April 21, 2014. Results showed participants treated with Cyramza experienced a median overall survival of 5.2 months compared to 3.8 months in participants receiving placebo. Additionally, participants who took Cyramza experienced a delay in tumor growth (progression-free survival) compared to participants who were given placebo.
Results from a second clinical trial that evaluated the efficacy of Cyramza plus paclitaxel - Taxol - (another cancer drug) versus paclitaxel alone also showed an improvement in overall survival.
Pending the results of this combination therapy and given your sister's metastses, your sister is probably going to have to begin palliative treatment soon. Please look up Cyramza here on www.drugs.com. Palliative means literally "to ease the pain;" "to relieve or lessen without curing."
Search for questions
Still looking for answers? Try searching for what you seek or ask your own question.
Updated 24 Aug 2009 • 1 answer
Updated 26 Jan 2019 • 6 answers
Updated 6 Apr 2016 • 1 answer
Updated 2 Jul 2016 • 1 answer
Updated 27 Nov 2018 • 1 answer