Stopped working at 60mg and doc said highest dose could take. I now withdrawing off them and ill as hell..they mixing 15mg of mirtazipine to help withdrawal... without any monitoring. Feeling ill... sick of doctors.have just undergone camera endoscopy twice due to mouth ulcers and stomach pain and my Dentist knew the tabs the prob once I told her the name... thinking my dentist more knowledgeable and may ask her and go chemist and give doctors a miss In future... my faith in them gone..I worse not better 54 yr female