My partner of 7 years lost his mind. He was slowly losing it for a year now, but his switch flipped completely within 4h on his trip to Thailand, and I suspect it is because he probably took some substance (I honestly don't know if he has an underlying condition, he has never been diagnosed though he has been to a psychologist several times before but they said it was stressed and gave him a book on mindfulness) He is going to be in Thailand now for 2 more weeks and I am fairly sure that no bodily harm will come to him so it can wait, but I am wondering this: which substance, if any, can cause mania like this? How long does it last? And how does it end? In depression or in psychosis or just go back to normal?