My friend took 15mg of roxicet @ 8am, then 4mg of subutex @ 2pm. Is there a possibility of an overdose? what other side effects should we look for?
Watch for signs of withdrawal symptoms. Subutex blocks opiates and may cause precipitaed withdrawals. The subutex also renders the roxicet usless.
oxycodone ↔ buprenorphine
Applies to: Roxicet (acetaminophen/oxycodone), Subutex (buprenorphine)
GENERALLY AVOID: Mixed agonist/antagonist analgesics may reduce the analgesic effect of pure opioid agonists and/or precipitate withdrawal symptoms in patients who have received or are receiving a course of therapy with a pure opioid agonist analgesic.
MANAGEMENT: Mixed agonist/antagonist analgesics such as pentazocine, nalbuphine, dezocine, butorphanol, and buprenorphine should generally be avoided or administered with caution to patients who have received or are receiving pure opioid agonists.
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