I am taking microbiology and am having a difficult time locating this information. I have completed my patient study except for this part!
If vancomycin is used in the course of treatment for endocarditis, a 6-week rather than 4-week course of therapy is recommended. Combination therapy is also recommended to treat enterococcal meningitis, usually for at least 2-3 weeks. Intravenous linezolid or intravenous plus intraventricular quinupristin-dalfopristin have also been used to successfully treat meningitis.
Here is the link to this info reference.medscape.com/drug/vancocin-vancomycin-342573
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