I took Zoloft for about 20 years and my primary physician just put me on Wellbutrin and discontinued the Zoloft. I was diagnosed with Narcolepsy in 2009 and have been taking Nuvigil 250 mg with some success. The reason I was placed on Wellbutrin is because I have been so tired and lethargic for the past 6 months; so much so that I fall asleep almost every evening after work. I also should mention that I have been taking Vitamin B12 shots for about 6 months and recently started taking Vitamin D 50000 capsules. Since beginning the Wellbutrin I am having trouble keeping my eyes open, I can't focus on work and I think I'm even slurring my words.