I have been taking Warfarin over a year and have stayed at 2.0 average. The last two check ups - four weeks apart I have been at 3.0. I don't want that number to go any higher - the only thing that has changed is that I was told to take lopermide because some of the other drugs I am on cause a big problem in that dept. I had a single left lung transplant in 2003 - in 2009 I had a blood clot in my lung and left leg. So I take warfarin.