This is what I found on the net about your question:
"There is a known interaction between Coumadin and alcohol. Alcohol intake can affect the medication in various ways. A consistent, moderate intake (such as one drink per day) is usually okay for most people. However, binge drinking or even "saving up" your daily drinks for the weekend can increase the risk of bleeding -- including dangerous internal bleeding. Chronic, significant alcohol use, such as with alcoholism, can have the opposite effect, making Coumadin less effective by increasing the risk of blood clots, while at the same time increasing the risk of gastrointestinal bleeding. Be sure to talk with your healthcare provider about an alcohol intake that is safe and acceptable to you."
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