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How does simvastatin, aspirin, atenolol, ramipril, thiazide reduce the risk of chd?

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suzanne66 5 Apr 2012

Coronary heart disease (CHD), also called coronary artery disease or coronary vascular disease, is a condition in which plaque builds up inside the coronary arteries. These arteries supply oxygen-rich blood to your heart muscle.
Plaque is made up of fat, cholesterol, calcium, and other substances found in the blood. When plaque builds up in the arteries, the condition is called atherosclerosis. The buildup of plaque occurs over many years.
Over time, plaque hardens and narrows your coronary arteries. This limits the flow of oxygen-rich blood to your heart muscle.
Eventually, an area of plaque can rupture (break open). This causes a blood clot to form on the surface of the plaque. If the clot becomes large enough, it can mostly or completely block blood flow through a coronary artery.
If the flow of oxygen-rich blood to your heart muscle is reduced or blocked, angina or a heart attack may occur.
Over time, CHD can weaken the heart muscle and lead to heart failure and arrhythmias. Heart failure is a condition in which your heart can't pump enough blood to meet your body’s needs. Arrhythmias are problems with the rate or rhythm of the heartbeat.

Your medicines work in different ways to reduce the risk and complications of CHD (angina, heart attack, heart failure or arrhythmias)
Ramipril - lowers blood pressure and protects your heart and kidneys.
Aspirin - helps prevent blood clots from forming in your arteries.
Atenolol - lowers heart rate, blood pressure, and oxygen use by the heart
Thiazide - lowers blood pressure and treats heart failure

I hope this is of help.
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