I've been on effezor 16 years. It helps me tremendously w/ anxiety and severe depression. None of the risks of effexor were known @ the time I began taking it.. My Dr. said since it is so effective for me, there is no reason to try and get off it. I'm sure I'm going to be an Effexor XR lifer. Opinions/ideas on me staying on it for life? I'd love the feedback. Thanks!