YES YOU SHOULD! Dangerous combination! Mixing those two drugs can easily cause a horrible condtion known as "serotonin syndrome" which has a long list of very bad effects-both from a mental/psychiatric and body/physical standpoint. Google search "Serotonin Syndrome" or better yet call a pharmacist at a pharmacy who isn't too busy to give you their attention about your two prescribed drugs. In the meantime, do not mix them until your doctors and at least one experienced pharmacist say it's completely safe to mix the 2 meds. I have a feeling that you will be told not to. I'd bet the automated drug interaction checker on this site will agree with me. Never mix a "triptan" with a SSRI! You're better off with the migranes. Let me guess-You have at least 2 doctors and neither one knows what meds you are prescribed by the other doctor... Am I right?
No it is not worth it to have migraines. Seratonin Syndrome is a very rare condition. I also take Protonix, Maxalt (no more than 2 days a week), and 2 other medications that all can cause Seratonin Syndrome for the past 5 years with no problem. My doctor did take me off of the Tramadol due to the problem. But I am taking a top dose of one of the Seratonin Syndrome meds. My excellent internal medicine doctor told me that the condition was rare and if I had any of the symptoms of Seratonin Syndrome to go to the ER to have it treated. And I have also been evaluated by a top educated pharmacologist (forget her exact qualifications) who also saw no problem with my meds. Yes, talk to your doctor about it, but I wouldn't worry at all.
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