I've been on the fentanyl 50mcg patch along with 3 7.5/375mg Hydrocodones per day for abdominal pain for a while, and my tolerance has pretty much skyrocketted (I was on strong opiates for several years a while back due to almost 10 abdominal surgeries). The last visit with my pain Dr, he said we might try switching medications to ones that'll use different receptors. My question is, what kind of meds would that encompass? Or, what would a doctor prescribe to someone who has huge tolerance to synthetic opiates?